Integration of the Beckman Coulter Vi-CELL BLU Cell Viability Analyzer into the Sartorius Ambr® 250 High Throughput for automated determination of cell concentration and viability
The Vi-CELL BLU Analyzer stands at the forefront of cellular analysis, providing cutting-edge solutions for cell viability assessment in the field of biotechnology and cell culture. Leveraging advanced imaging technology, the Vi-CELL BLU analyzer offers accurate and reliable cell counts, viability, and concentration measurements.
By automating the monitoring of key cell culture parameters with the integrated Vi-CELL BLU analyzer and Sartorius Ambr® 250 High Throughput Bioreactor & Ambr® 15 Cell Culture Systems, you can reduce manual process steps, minimizing the risk of contaminating samples and increasing the speed and reliability of analysis of critical cell culture parameters .
The automation ensures that cell viability and count data is consistently accurate and reproducible , providing you with the confidence needed to make reliable decisions for your process.
Enhancing Cell Culture Workflows by connecting Vi-CELL BLU to Ambr® mini bioreactors systems
Seamless integration
Enables at-line measurement of cell viability, concentration, and other vital parameters that are key to the cell culture process to be regularly scheduled.
Enhanced Data Analysis
Easily correlate cell culture analytics with process conditions. This facilitates better decision-making for process optimization and improved productivity.
Standalone Mode
The Vi-CELL BLU analyzer can still be used in standalone mode for ad-hoc measurements if needed.
Workflow Optimization
Elimination of manual sample handling reduces risk of human error to help ensure consistent and reliable results.
Scalability
As cell culture processes move from development to larger-scale production, the integration of Vi-CELL BLU analyzer and Sartorius Ambr® 250 High Throughput or Ambr® 15 Cell Culture instruments helps ensures a smooth transition.
Application Note: Comparative Analysis of Online and Offline Cell Viability in Sartorius Ambr® 250 High Throughput Bioreactor Using Vi-CELL BLU Analyzer
In this application note, we provide data from cultivations performed in a Sartorius Ambr® 250 High Throughput Bioreactor system which were sampled daily on an integrated Vi-CELL BLU analyzer to determine cell concentration and viability online. These results are compared with offline values. The integrated Vi-CELL BLU Cell Viability Analyzer was installed at Boehringer Ingelheim Pharma GmbH & Co. KG (Biberach, Germany); the data shown in this application note was obtained during beta testing of the integration at their facilities. We would like to thank Boehringer Ingelheim GmbH & Co. KG and its respective employees for the successful collaboration.