Enhancing IVF Laboratory Success Through Precision and Quality
In vitro fertilization (IVF) is a widely used assisted reproductive technology (ART) designed to help couples overcome infertility. IVF involves fertilizing an egg with sperm outside the body, followed by embryo culture for 2–6 days before transfer to the uterus, with the goal of achieving a successful pregnancy.
Even the slightest deviation in environmental or procedural parameters can compromise embryo development and reduce pregnancy success. This is why precision, stability, and reproducibility are critical at every stage of the IVF workflow.
Together with its partners, Analis provides local expertise and support for state-of-the-art equipment designed to meet both current and future needs of IVF laboratories.
Advanced IVF Equipment by Esco Medical
Esco Medical is a leading manufacturer and innovator of high-quality IVF equipment, including:
- Long-term embryo incubators
- Time-lapse incubators
- ART workstations
- Anti-vibration tables
Esco Medical continuously develops advanced technologies to support the growing demands of IVF laboratories. Solutions such as the MIRI® Evidence Witnessing & Traceability System and the integration of Artificial Intelligence (AI) for embryo selection illustrate this commitment.
Microscopy: A Core Element of IVF Workflows
Microscopy plays a central role in IVF procedures, including:
- Gamete selection
- Sperm evaluation
- Micromanipulation (ICSI / IMSI)
- Embryo observation
The EVIDENT IX73 ICSI/IMSI inverted microscope is a core tool in assisted reproduction, providing high-contrast imaging and stability for delicate manipulations. Combined with stereo microscopes, it delivers a complete micro-imaging solution for accurate and efficient IVF workflows.
IVF as a Fertility Treatment
IVF can support patients facing challenges such as blocked fallopian tubes, low sperm count, or genetic disorders. However, IVF also involves medical risks and ethical considerations, including multiple pregnancies, ovarian hyperstimulation syndrome, and emotional stress related to treatment outcomes.
MIRI® Evidence: Automated Witnessing & Traceability
The MIRI® Evidence system enhances embryo culture safety through automated witnessing and traceability. Its multiroom incubator design, real-time monitoring, and advanced data analytics help optimize embryo development while improving workflow efficiency in reproductive laboratories.
Discover the videoLearn more
Artificial Intelligence in ART
The integration of AI in Assisted Reproductive Technology offers new possibilities for embryo selection. By supporting embryologists with automated morphological analysis, AI helps reduce subjectivity and variability in embryo grading, ultimately supporting higher pregnancy success rates.
Learn about AI in ART from 1955 until todayHow AI Supports Embryo Selection
Traditional embryo assessment relies on visual evaluation of morphology and developmental dynamics, particularly at the blastocyst stage. These assessments are inherently subjective and influenced by observer experience.
AI-driven image analysis offers a complementary approach by analyzing morphological features such as the inner cell mass (ICM) and trophectoderm (TE), supporting more consistent and data-driven decision-making.
Adapted from: JM Raimundo, P Cabrita, "Artificial intelligence at assisted reproductive technology," Procedia Computer Science, Volume 181, 2021, Pages 442-447, ISSN 1877-0509, DOI: 10.1016/j.procs.2021.01.189. Full Article.
Imaging Systems for ICSI and IMSI
CSI and IMSI require exceptional precision and stability. The EVIDENT IX73 ICSI/IMSI inverted microscope provides:
- High-contrast imaging for sperm and oocytes in plastic culture dishes
- Relief contrast optics
- Optional DIC or polarized light modules for non-invasive spindle observation
View IX73 specifications and download brochure
For oocyte preparation, the EVIDENT SZX16 research stereomicroscope offers ergonomic, high-resolution imaging. Together, these systems form a complete microscopy solution for assisted reproduction.
View BX53 specifications and download brochure
View SZX16 specifications and download brochure
Contact our IVF microscopy experts
Reproductive Health Assays and Diagnostic Solutions
Beckman Coulter offers a comprehensive portfolio of reproductive health assays available on its immunoassay analyzers (Beckman Coulter Immunoassay analyzers), supporting the screening, diagnosis, and management of female-specific and age-related conditions.
- See also the Clinical Utility of Automated AMH Technology Discover more about immunoassays for reproductive health
- hLH
- Inhibin A
- Inhibin B (ELISA)†
- PAPP-A†
- Progesterone
- Prolactin
- Sensitive Estradiol
- Unconjugated Estriol
- SHBG
- Testosterone
- Total βhCG (5th IS)
- AFP (ONTD)
- AMH†
- DHEA-S
- hFSH
Our Product Categories in In Vitro Fertilization (IVF)
Our products
The MIRI® Time-Lapse Incubator is a multiroom incubator with a built-in camera and microscope. Designed and made in the EU, it delivers high-quality real-time time-lapse images of developing embryos, without removing them from the safety of the incubation chamber for manual microscopy. Time-lapse monitoring provides detailed morphokinetic data throughout development, which routine spot microscopy cannot. It captures all key events, helping IVF labs identify healthy embryos with the highest implantation potential and supporting higher pregnancy rates.
FEATURES:
Completely independent chambers
6 (TL6) or 12 (TL12) independent chambers with precise temperature and gas control: opening one chamber does not affect the others.
Time-lapse monitoring
Time-lapse video built from images allows objective, reliable scoring and annotation of embryos, for better prediction of development and implantation potential.
Heated lid
Strong uniformity between top and bottom. Heated chamber lids prevent condensation, improve temperature regulation and recovery, and keep temperature uniform between the top and bottom of the chamber.
Fast temperature and gas recovery
- Temperature recovery < 1 min
- Gas recovery < 3 mins
Superior gas system
- A built-in tri-gas mixer, an advanced gas regulation system and HEPA-VOC filtered recirculation allow precise gas control and lower gas consumption.
- UV sterilization of the recirculating gas ensures the biological safety of the embryos.
Easy external gas and temperature validation
Gas sampling ports for each chamber and independent PT-1000 sensors allow external quality evaluation of gas levels and temperature in each chamber.
User friendly interface
Touchscreen control panel with an intuitive menu to manage the device configuration.
The CultureCoin
The specially designed CultureCoin dish lets each chamber culture 14 embryos — a total of 84 for the TL6 and 168 for the TL12.
MIRI® TL Data Logger
Continuously monitors and records gas flow, gas concentration and pressure, and temperature regulation.
Continuous pH monitoring
Optional SAFE Sens integration for continuous pH monitoring without opening the chamber.
MIRI® TL Viewer software and MIRI® TL Data Server
- Greatly increase image and data storage capacity by adding the MIRI® TL Data Server.
- Add the MIRI® TL Viewer software platform to review, annotate and compare embryo morphokinetics and export data for retrospective analysis.
Advanced upright fluorescence microscope tailored for life science research and clinical diagnostics.
Designed for flexibility and precision, the BX53 offers a modular semi-motorized platform ideal for fluorescence imaging, brightfield, and specialized contrast techniques.
- High-luminosity True Color LED illumination ensures consistent color temperature across all modes
- Modular system: motorize only what you need (focus, condenser, nosepiece)
- Compatible with a wide range of contrast methods including fluorescence, DIC, and polarization
- Integrates with Olympus / Evident X Line objectives for exceptional flatness, contrast, and chromatic correction
- Easily configured for educational, clinical, or research multi-user environments
Ideal for biomedical labs, tissue analysis, and pathology. Contact Analis experts in Belgium, the Netherlands, or Luxembourg for tailored advice and setup.
High-Precision Imaging for Advanced Reproductive Research
Why Choose the IX73 for ICSI/IMSI?
- Designed for IVF: Optimized for ICSI, IMSI, and SL-ICSI techniques.
- Improved Workflow: Motorized switching between objectives and condenser positions with one-button operation.
- High-Contrast Imaging: Supports relief-contrast and differential interference for clear oocyte and sperm visualization—even in plastic dishes.
- Effortless Operation: Focus and brightness automatically adjust with magnification changes.
- Expandable Configuration: Compatible with third-party micromanipulators and accessories.
Application Highlights
ICSI (Intracytoplasmic Sperm Injection)
IMSI (Intracytoplasmic Morphologically Selected Sperm Injection)
SL-ICSI (Spindle Localization)
Key Features
- Semi-motorized microscope with motorized switching of condenser/objectives
- Spindle observation standard (polarized light)
- One-button switching between observation methods via hand switch
- Supports IMSI with optional unit
- UIS2 optical system for superior image quality
- Compatible with relief contrast, DIC, and polarization techniques
Looking for full automation?
Inverted compound microscope for standard multicolor fluorescence and routine imaging.
The Olympus / Evident IXplore IX73 is optimized for high-quality imaging with ergonomic design.
- Fluorescence-ready system for cell culture and standard research tasks
- Same optical quality as high-end IXplore platforms
- Encoded upgrade path for improved reproducibility
- Simplified, intuitive operation for efficient workflow
- Modular build supports different vessels and observation techniques
Designed for consistent results in routine lab work. Contact Analis for full system integration.
Inverted Microscope for Live-Cell Imaging and Automation
Motorized and Modular Design for Precision Imaging
Seamless integration with Olympus cellSens software ensures intuitive operation, automated workflows, and consistent image acquisition across experiments.
Flexible Configurations for Time-Lapse and High-Content Applications
- Supports fluorescence, DIC, phase contrast, and IR-DIC imaging
- Motorized Z-drive and XY stage with TruFocus™ Z-drift compensation
- Modular deck structure for easy integration of additional optical paths or accessories
- Seamless compatibility with incubation systems for live-cell viability
- Ideal for cancer biology, stem cell tracking, and neuroscience research
- Scalable for routine imaging to AI-assisted image acquisition and automated analysis
The IXplore IX85 platform is also available in two optimized configurations:
- IXplore IX85 Pro for high-speed, high-content imaging with a wide field of view
- IXplore IX85 Live for long-term live-cell imaging with minimized phototoxicity and precise environmental control.
The MIRI® II Multiroom Incubator dedicates one chamber for one patient. IVF lab can choose from models having 6 or 12 chambers that are completely independent of each other. Any disruption on one chamber (e.g. temperature drop after opening the lid) has zero impact on the rest of the system. It has a touchscreen PC to control and monitor important parameters (temperature, gas concentration) simultaneously and give visual and audible alarm to signal critical conditions.
FEATURES:
1. One Chamber - One Patient
2. Superior gas system
3. Heated lid
4. Fast temperature and gas recovery
5. Touchscreen PC
6. Optimized heating plates
7. Easy external validation
8. Full-featured data logging software
SAFE Sens pH monitoring system for IVF culture media is integrated as a standard feature. In the US, every MIRI® II-12 unit will come equipped to easily turn on the pH monitoring feature. The SAFE Sens provides the following benefits over conventional pH tools:
(a) a decrease in time spent on pH protocols,
(b) data trending to optimize media pH equilibration time,
(c) having out-of-range email alert system, and
(d) being non-invasive due to the non-usage of petri dish and the constant opening of the incubator.
Multiroom incubator for embryo culture with 6 independent chambers, preventing cross contamination without causing any disturbance to the neighboring chambers even when the lids are opened/closed.
The MIRI is the actual standard system in new IVF labs.
DELIVERY INCLUDES:
-1 pc HEPA+VOC filter
-2 pcs External in-line filters
-2 pcs Fast connector with 15cm silicone tubing
-1 pc Data extension cable (1.5m)
-1 pc USB key with Data logging software
-1 pc power cable
-6 pcs heating optimization plates for Falcon, Nunc, or Vitrolife (please specify at the order the type of plate holder to be included)
FEATURES:
Six (6) completely independent chambers
Six independent MIRI® chambers, with precise temperature and gas regulation: Opening any chamber does not affect the environment in other chambers. Temperature or gas fluctuation caused by opening the lid have no impact on the rest of the system.
Superior gas system
Works with premix gas or 100% CO2 gas, with NDIR CO2 sensor to regulate CO2 levels. HEPA-VOC gas filtration system ensure clean gas recirculation
Heated lid
Heated chamber lids prevent condensation, enhance temperature regulation/recovery, and ensure temperature uniformity between the top and bottom of the chamber.
Fast temperature and gas recovery
Temperature recovery <1 min
Gas recovery <3 mins.
LED display
Large easy to read LED display and easy to navigate menu.
Optimized heating plates
Heating plate inserts to fit commonly used embryo culture dishes.
Easy external validation
Gas sampling ports for each chamber and independent PT-1000 sensors allow external quality evaluation of gas levels and temperature in each chamber.
MIRI® Data Logger
Continually monitors and documents gas flow, gas concentration and pressure, and temperature regulation.
Audible alarms for out of range parameters, with alarm logs documented in the Data Logger.
Space-saving the touchscreen tablet and stacking frame
Maximise the laboratory workplace by letting go of bulky computers and saving space with a tablet and a MIRI® stacking frame. Real time parameters such as temperature, gas concentration points, gas input pressures, gas flow rates, and even pH measurement can be conveniently viewed through the touchscreen tablet.
Continuous pH monitoring
Optional SAFE Sens integration for continuous pH monitoring without opening the chamber.
Advanced stereomicroscope platform for zoom imaging from whole organisms to cellular details.
The Olympus / Evident SZX16 offers a powerful zoom ratio and precision optics for complex life science research tasks.
- Zoom ratio of 16.4:1 enabling magnification up to 230x
- Apochromatic optics ensure clarity with minimized chromatic aberration
- Supports fluorescence, darkfield, brightfield, and polarization observations
- High NA objectives deliver up to 900 line pairs/mm resolution
- Ergonomically designed with ample working space for micromanipulation
Ideal for developmental biology, embryology, and neuroscience. Local support from Analis is available across Benelux.
Color digital camera optimized for clinical and life science imaging tasks.
The Olympus / Evident DP23 delivers high-quality color reproduction with ease of use.
- Crisp, clear imaging for routine documentation and teaching
- Enables live viewing and fast capture on large screens
- DP23-AOU option allows networked image sharing
- Compatible with Olympus microscopes and software
- Suitable for clinical, education, and research labs
A balanced choice for high-quality routine imaging. Available via Analis.
Versatile color camera for brightfield and fluorescence imaging in a single device.
The Olympus / Evident DP75 supports high-resolution imaging and complex staining applications.
- Supports wavelengths up to 1000 nm with switchable IR cut filter
- TruAI denoising enhances live image quality
- Vivid color reproduction with excellent sensitivity
- Streamlined capture of brightfield and fluorescence images
- Ideal for research labs needing multi-modal imaging
Optimize imaging with a single smart camera. Ask Analis for expert support.
Smart digital camera that transforms any microscope into a wireless teaching tool.
The Olympus / Evident EP50 enables collaborative viewing and digital streaming from microscope to screen.
- Full standalone configuration via tablet or PC
- Simultaneous WLAN and HDMI output
- Supports wireless sharing to monitors or projectors
- Designed for teaching, group learning, and live demonstration
- Easy integration with Olympus microscope systems
Empower classrooms and training with connected microscopy. Available through Analis.
Related
The MIRI® Time-Lapse Incubator is a multiroom incubator with a built-in camera and microscope. Designed and manufactured in EU, the MIRI® Time-Lapse Incubator provides high quality time-lapse images of embryos developing in "real-time" without having to remove the embryos from the safety of the incubation chamber for manual microscopy. Time-lapse embryo monitoring provides detailed morphokinetic data throughout embryo development, which is not available on routine spot microscopic evaluation. This allows all important events to be observed, helping IVF labs to identify healthy embryos with the highest probability of implantation, with the aim of achieving higher pregnancy rates. FEATURES: Completely independent chambers 6 (TL6) / 12 (TL12) independent chambers with precise temperature and gas regulation: Opening any chamber does not affect the environment in other chambers. Time-lapse monitoring Time-lapse video generated from images allows objective and reliable scoring and annotation
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