Pilot Freeze Dryers
Designed for Process Optimisation and Small-Batch Production
Pilot freeze dryers are specifically designed for process development, optimisation, and small-batch series production. They represent the ideal solution for scale-up activities prior to full industrial manufacturing.
Users can select from several models covering product capacities from 4 kg to 16 kg per drying cycle, with temperature-controlled shelf areas ranging from 0.11 m² to 1.2 m².
Each lyophilizer delivers reliable and reproducible freeze-drying results for solid or liquid products in a wide variety of containers. Thanks to similar geometries, comparable temperature control systems, and identical user interfaces, pilot units follow the same design philosophy as large production units freeze dryers.
All models feature detailed yet intuitive process control, combined with the integration of advanced Process Analytical Technologies (PAT tools)—a key requirement for development and optimisation work.
These pilot systems are used across a wide range of industries, with a strong focus on pharmaceutical and biotechnology applications.
Listen to our customers sharing their experience
Hear from our customer JRC Geel, a long-standing Martin Christ partner since 1985, as they share their experience with the E2-65D Pilot Freeze Dryer featuring Air-CO₂ cooling.
About JRC Geel
Since 1962, the Joint Research Centre (JRC) of the European Commission site in Geel (Belgium) has brought together multidisciplinary scientific expertise to develop new measurement methods and reference materials.
Geel is one of the six scientific sites of the JRC and plays a key role in promoting standardisation and harmonisation across the European Union, supporting innovation while protecting consumers and citizens.
The JRC Geel site employs approximately 280 specialists working on reference materials and measurement science.
We would like to sincerely thank Jean Charoud-Got and Håkan Emteborg for welcoming us into their laboratory and for sharing their valuable feedback and experience. As part of a continuous improvement process, both for us and our suppliers, customer feedback is essential to ensure the relevance, performance, and reliability of our solutions.
Optimising Lyophilisation Processes for Oligonucleotides and APIs Under GMP Conditions
Eurogentec Shares Its Experience
How can a lyophilisation process for oligonucleotides and active pharmaceutical ingredients (APIs) be optimised while complying with GMP standards?
Why choose freeze-drying, and why perform it in a cleanroom under laminar flow?
This is what the Eurogentec laboratory explains, sharing its experience and best practices with us.
Eurogentec, part of the KANEKA Corporation, is a Belgian biotechnology company providing life science products and customised services to academic, medical, and industrial scientists worldwide. The company is also widely recognised for the development and production of biopharmaceutical critical raw materials and therapeutic molecules.
We would like to thank Olivier Bosch and Véronique Makaire for welcoming us into their laboratory and for sharing their valuable feedback and expertise.
As part of a continuous improvement approach, both for us and our suppliers, customer feedback plays a key role in strengthening process quality, compliance, and performance.
Our products
The Martin Christ Epsilon 1-4 LSCplus is a compact, high-performance freeze dryer designed for pilot-scale lyophilization in pharmaceutical, biotechnology, and research laboratories. Equipped with the LSCplus control system, this model ensures precise, reproducible results for small-scale production and process development. With a compact design and advanced process control, it is ideal for applications requiring high-quality freeze-drying of sensitive materials such as biologics, food ingredients, and active pharmaceutical ingredients (APIs).
Key Features and Technical Specifications
- Condenser Capacity: 4 kg ice capacity, 3 kg/24 h sublimation rate – optimized for small-scale, high-throughput lyophilization
- Temperature Control:
- Shelf Temperature Range: -60°C to +60°C – precise and stable temperature control for sensitive products
- Condenser Temperature: -85°C – ensures efficient sublimation and optimal sample drying
- Shelf Area: 0.52 m² – compact design suitable for vials, flasks, or small bulk samples
- Vacuum System:
- Dry-running vacuum pump for clean and contamination-free operation
- Capacitive vacuum sensor for accurate vacuum measurement
- Process Control:
- LSCplus control system with intuitive touchscreen, real-time monitoring, and customizable cycles
- Integrated product temperature probes for real-time process monitoring and optimization
- Chamber Configuration:
- Corrosion-resistant stainless steel for durability and easy cleaning
- Customizable shelf configurations to accommodate various sample types
- Data Logging and Connectivity:
- Real-time data logging for complete process documentation
- USB and Ethernet interfaces for seamless data export and remote control
- Safety Features:
- Explosion-proof design (optional) for use with flammable solvents
- Closed-loop cooling system to minimize solvent loss and ensure environmental safety
Compliance and Application Areas
The Epsilon 1-4 LSCplus is designed to meet GMP and FDA guidelines, making it ideal for a variety of applications, including:
- Pharmaceutical lyophilization – formulation development, stability testing, and API drying
- Biotechnology applications – enzyme stabilization, cell culture preservation, and protein lyophilization
- Material science – drying of nanomaterials, polymers, and advanced materials
- Food and nutraceuticals – freeze-drying of bioactive compounds, ingredients, and nutraceutical formulations
Why Choose the Martin Christ Epsilon 1-4 LSCplus?
- Compact and efficient design – ideal for laboratories with limited space
- Advanced LSCplus control system for precise and reproducible lyophilization cycles
- Flexible and scalable for both small-scale development and process optimization
- Safe and GMP-compliant for use in regulated industries such as pharmaceuticals and biotechnology
The Epsilon 1-4 LSCplus offers a compact, high-performance freeze-drying solution for labs seeking precise and reproducible results in a range of scientific and industrial applications.
Get a Quote or More Information
For pricing, availability, or technical inquiries, contact us today or request a personalized consultation to discuss your specific lyophilization needs.
The Martin Christ Epsilon 2-4 LSCplus is a pilot-scale freeze dryer designed for reliable, efficient lyophilization in pharmaceutical, biotechnology, and research laboratories. Featuring the LSCplus control system, it provides precise, reproducible lyophilization cycles with real-time process monitoring and advanced temperature and vacuum control. This model is ideal for small to medium-scale production, formulation development, and research applications requiring high-quality freeze-drying of sensitive materials, such as biologics, APIs, and food products.
Key Features and Technical Specifications
- Condenser Capacity: 4 kg ice capacity, 3.5 kg/24 h sublimation rate – optimized for small- to medium-scale lyophilization processes
- Temperature Control:
- Shelf Temperature Range: -60°C to +60°C – precise control of sample temperature to ensure optimal drying conditions
- Condenser Temperature: -85°C – efficient solvent trapping and sample sublimation for high-quality results
- Shelf Area: 0.52 m² – suitable for drying vials, flasks, and small bulk samples
- Vacuum System:
- Dry-running vacuum pump for clean, contamination-free operation
- Capacitive vacuum sensor for accurate pressure monitoring throughout the process
- Process Control:
- LSCplus control system with touchscreen interface, real-time monitoring, and customizable cycle programming
- Product temperature probes for accurate thermal monitoring of each sample during the freeze-drying cycle
- Chamber Configuration:
- Stainless steel interior for long-lasting durability and ease of cleaning
- Customizable shelf configurations for flexible sample handling and optimization
- Data Logging and Connectivity:
- Real-time data logging for precise documentation of the lyophilization process
- USB and Ethernet interfaces for easy data export, remote access, and integration with external systems
- Safety Features:
- Explosion-proof design (optional) for use with flammable solvents
- Closed-loop cooling system to minimize solvent loss and ensure environmental protection
Compliance and Application Areas
The Epsilon 2-4 LSCplus is designed to meet GMP and FDA guidelines, making it suitable for applications across various industries, including:
- Pharmaceutical lyophilization – formulation development, stability testing, and drying of APIs
- Biotechnology – enzyme stabilization, protein preservation, and cell culture processing
- Material science – drying of polymers, nanomaterials, and advanced coatings
- Food and nutraceuticals – freeze-drying of bioactive compounds, natural extracts, and food products
Why Choose the Martin Christ Epsilon 2-4 LSCplus?
- Compact and reliable design – ideal for pilot-scale and medium-scale lyophilization
- Advanced LSCplus control system for reproducible, precise cycle control and real-time process monitoring
- Flexible and scalable – suitable for a variety of applications, from research to small-scale production
- GMP-compliant and safe – explosion-proof option and secure operation for solvent-based applications
The Epsilon 2-4 LSCplus offers a high-performance freeze-drying solution that ensures precise, reproducible lyophilization for a range of applications in the pharmaceutical, biotechnology, and food industries.
Get a Quote or More Information
For pricing, availability, or technical inquiries, contact us today or request a personalized consultation to find the best freeze-drying solution for your research or production needs.
The Martin Christ Epsilon 2-6D LSCplus is a high-performance, pilot-scale freeze dryer designed for precise, scalable lyophilization in pharmaceutical, biotechnology, and material science applications. This model features the advanced LSCplus control system, ensuring optimal temperature, vacuum, and process monitoring for a wide range of applications, including drug development, biologic preservation, and advanced material research. It provides reliable, reproducible results in the drying of complex samples, offering high throughput and operational flexibility.
Key Features and Technical Specifications
- Condenser Capacity: 6 kg ice capacity, 4.5 kg/24 h sublimation rate – ideal for high-volume, pilot-scale lyophilization applications
- Temperature Control:
- Shelf Temperature Range: -60°C to +60°C – precise and stable temperature control to meet the needs of temperature-sensitive materials
- Condenser Temperature: -85°C – effective trapping of sublimed solvents for high-quality results
- Shelf Area: 0.76 m² – versatile shelf configuration, ideal for large vials, flasks, or bulk sample drying
- Vacuum System:
- Dry-running vacuum pump for clean, contamination-free operation
- Capacitive vacuum sensor for accurate vacuum measurement and precise process control
- Process Control:
- LSCplus control system with intuitive touchscreen interface, real-time data monitoring, and customizable cycle programming
- Integrated product temperature probes for monitoring temperature profiles throughout the drying cycle
- Chamber Configuration:
- Stainless steel interior for durability, solvent resistance, and ease of cleaning
- Customizable shelf arrangements for diverse sample types, enhancing process flexibility
- Data Logging and Connectivity:
- Real-time data logging for accurate process documentation and reporting
- USB and Ethernet interfaces for seamless data export, remote access, and external system integration
- Safety Features:
- Explosion-proof design (optional) for use with flammable solvents
- Closed-loop cooling system to prevent solvent loss and maintain environmental protection
Compliance and Application Areas
The Epsilon 2-6D LSCplus is built to meet GMP and FDA standards, making it perfect for a range of critical applications, including:
- Pharmaceutical lyophilization – drying of APIs, drug formulations, biologics, and vaccines
- Biotechnology – preservation of enzymes, proteins, and cell cultures
- Material science – drying of sensitive materials such as nanomaterials, polymers, and coatings
- Food and nutraceuticals – freeze-drying of bioactive compounds, extracts, and food ingredients
Why Choose the Martin Christ Epsilon 2-6D LSCplus?
- High capacity and throughput – ideal for pilot-scale lyophilization with large sample volumes
- Advanced LSCplus control system for precise, reproducible cycles and real-time process management
- Flexible and scalable – suitable for diverse applications across pharmaceuticals, biotechnology, and material science
- Safety and GMP-compliant design – explosion-proof option and environmental protection for solvent-based applications
The Epsilon 2-6D LSCplus is the perfect solution for high-performance, scalable lyophilization, ensuring optimal drying results for a variety of applications requiring precision, reliability, and safety.
Get a Quote or More Information
For pricing, availability, or technical inquiries, contact us today or request a personalized consultation to discuss how the Epsilon 2-6D LSCplus can support your freeze-drying needs.
The Martin Christ Epsilon 2-6D Solvent is a pilot-scale freeze dryer specifically designed for lyophilization of solvent-based formulations in pharmaceutical, biotechnology, and chemical research. Featuring a high-performance condenser system, optimized vacuum technology, and precise temperature control, this model ensures safe and efficient freeze-drying of sensitive materials, including organic solvents and high-value APIs.
Key Features and Technical Specifications
- Condenser Capacity: 6 kg ice capacity, 4 kg/24 h sublimation rate – optimized for solvent-based applications
- Solvent Compatibility: Designed for organic solvent lyophilization, including ethanol, methanol, acetonitrile, and DMSO
- Temperature Control:
- Shelf Temperature Range: -60°C to +60°C – precise thermal control for solvent drying processes
- Condenser Temperature: -105°C – ensures effective solvent trapping and prevents vapor breakthrough
- Shelf Area: 0.52 m² – accommodates vials, flasks, and bulk samples
- Vacuum System: Solvent-compatible dry-running vacuum pump for contamination-free operation
- Process Control:
- LSCplus control system with intuitive touchscreen operation, real-time monitoring, and programmable drying cycles
- Capacitive vacuum sensor for accurate pressure measurement
- Product temperature probes for precise monitoring of thermal profiles
- Chamber Configuration:
- Stainless steel construction for chemical resistance and long-term durability
- Customizable shelf configurations for flexible sample handling
- Safety Features:
- Explosion-proof design (optional) for handling flammable solvents
- Closed-loop cooling system to prevent solvent loss and environmental contamination
Compliance and Application Areas
The Epsilon 2-6D Solvent is designed to meet GMP and FDA guidelines, making it suitable for:
- Pharmaceutical and biotech applications – lyophilization of solvent-based drug formulations and active ingredients
- Chemical research – drying of sensitive or volatile compounds requiring precise control
- Material science – processing of nanomaterials and polymer-based formulations
- Food and nutraceuticals – freeze-drying of solvent-extracted natural compounds
Why Choose the Martin Christ Epsilon 2-6D Solvent?
- Optimized for solvent-based freeze drying with high-efficiency solvent trapping
- Advanced process control with LSCplus for reproducible lyophilization cycles
- Safe and contamination-free operation with solvent-compatible vacuum technology
- GMP-compliant and scalable – ideal for process development and small-scale production
The Epsilon 2-6D Solvent is an excellent choice for laboratories and research facilities requiring a specialized freeze dryer for solvent-based applications, ensuring high precision, safety, and efficiency in lyophilization.
Get a Quote or More Information
For pricing, availability, or technical inquiries, contact us today or request a personalized consultation to find the right freeze-drying solution for your application.
The Martin Christ Epsilon 2-10D LSCplus is a high-performance pilot-scale freeze dryer designed for reproducible lyophilization in pharmaceutical, biotechnology, and research laboratories. Featuring the innovative LSCplus control system, this freeze dryer provides precise temperature, vacuum, and process monitoring for demanding applications such as drug formulation development, material science, and biological sample preservation.
Key Features and Technical Specifications
- Condenser Capacity: 10 kg ice capacity, 6 kg/24 h sublimation rate – optimized for large sample volumes
- Temperature Control:
- Shelf Temperature Range: -60°C to +60°C – precise and stable temperature regulation for sensitive materials
- Condenser Temperature: -85°C – efficient freezing and sublimation processes for high-quality results
- Shelf Area: 0.98 m² – ideal for vials, flasks, and bulk sample drying
- Vacuum System:
- Dry-running vacuum pump for clean, contamination-free operation
- Capacitive vacuum sensor for accurate pressure measurement
- Process Control:
- LSCplus control system with touchscreen interface, real-time monitoring, and customizable cycle programming
- Integrated product temperature probes to track the drying process in real-time
- Chamber Configuration:
- Stainless steel interior for durability, chemical resistance, and easy cleaning
- Customizable shelf configuration for flexible sample handling and increased throughput
- Data Logging and Connectivity:
- Real-time data logging for process monitoring
- USB and Ethernet interfaces for data export and remote control
- Safety Features:
- Explosion-proof design (optional) for handling flammable solvents
- Closed-loop cooling system to prevent loss of solvent and ensure environmental safety
Compliance and Application Areas
The Epsilon 2-10D LSCplus meets GMP and FDA standards, making it suitable for a wide range of applications, including:
- Pharmaceutical lyophilization – for drug formulations, biologics, and API stabilization
- Biotechnology applications – enzyme preservation, vaccine development, and cryopreservation of cell cultures
- Material science research – processing of nanomaterials, polymers, and coatings
- Food and nutraceuticals – precise freeze-drying of bioactive compounds and food ingredients
Why Choose the Martin Christ Epsilon 2-10D LSCplus?
- Advanced LSCplus control system for precise and reproducible lyophilization processes
- Efficient and scalable solution for process development and small-scale production
- High-quality, reproducible results with precise temperature and vacuum control
- Safe and GMP-compliant design for pharmaceutical, biotech, and research applications
The Epsilon 2-10D LSCplus is the perfect solution for laboratories seeking advanced, precise, and scalable freeze-drying technology, ensuring high-efficiency lyophilization for a wide variety of applications.
Get a Quote or More Information
For pricing, availability, or technical inquiries, contact us today or request a personalized consultation to discuss your freeze-drying needs.
The Martin Christ Epsilon 2-10D Solvent is a pilot-scale freeze dryer specifically designed for solvent-based lyophilization in pharmaceutical, biotechnology, and chemical research. With an advanced -105°C condenser, high-performance vacuum system, and customizable shelf configurations, this model ensures safe, efficient, and reproducible drying of materials containing organic solvents such as ethanol, methanol, acetonitrile, and DMSO.
Key Features and Technical Specifications
- Condenser Capacity: 10 kg ice capacity, 6 kg/24 h sublimation rate – ideal for solvent-based freeze-drying applications
- Solvent Compatibility: Optimized for organic solvent lyophilization, preventing vapor breakthrough
- Temperature Control:
- Shelf Temperature Range: -60°C to +60°C – precise thermal control for solvent drying processes
- Condenser Temperature: -105°C – efficient solvent trapping for high-performance drying
- Shelf Area: 0.98 m² – accommodates vials, flasks, and bulk samples
- Vacuum System:
- Solvent-compatible, dry-running vacuum pump for contamination-free operation
- Capacitive vacuum sensor for precise pressure monitoring
- Process Control:
- LSCplus control system with intuitive touchscreen operation, real-time data logging, and programmable drying cycles
- Product temperature probes for accurate thermal profiling
- Chamber Configuration:
- Stainless steel construction for maximum durability and solvent resistance
- Flexible shelf configurations for diverse sample types
- Safety Features:
- Explosion-proof design (optional) for handling flammable solvents
- Closed-loop cooling system to prevent solvent loss and environmental contamination
Compliance and Application Areas
The Epsilon 2-10D Solvent meets GMP and FDA guidelines, making it suitable for:
- Pharmaceutical and biotech applications – lyophilization of solvent-based drug formulations, vaccines, and biologics
- Chemical research – drying of volatile or temperature-sensitive compounds
- Material science – processing of nanomaterials, polymers, and coatings
- Food and nutraceuticals – freeze-drying of solvent-extracted natural products and bioactive compounds
Why Choose the Martin Christ Epsilon 2-10D Solvent?
- Specifically designed for solvent-based lyophilization with superior solvent trapping
- Advanced LSCplus process control for reproducible, high-precision drying cycles
- Safe and contamination-free operation with solvent-compatible vacuum technology
- Scalable and GMP-compliant – ideal for process development and small-scale production
The Epsilon 2-10D Solvent is the perfect solution for laboratories and research facilities requiring high-precision, solvent-compatible freeze drying, ensuring maximum efficiency, reproducibility, and safety.
Get a Quote or More Information
For pricing, availability, or technical inquiries, contact us today or request a personalized consultation to find the right freeze-drying solution for your application.
