Beckman Coulter Life Sciences, is the supplier of the Solid Phase Reversible Immobilization (SPRI) technology, widely known as the science behind AMPure XP. This technology has become the gold standard for clean-up of nucleic acids in next generation sequencing (NGS) and is the most cited and used clean-up kit within the NGS market. SPRI paramagnetic beads selectively bind nucleic acids by size.
We provide 4 different chemistries for nucleic acid cleanup and size selection. All these chemistries can be used manually or fully automated on our batch instruments or Biomek liquid handlers.
AMPure XP Bead
Based Reagent
The gold standard in bead-based, next-generation sequencing (NGS) cleanup—in fact, it's suggested in over 200 library preparation kits from trusted sequencing companies.
SPRIselect Bead-Based Reagent
Suggested in over 40 NGS library preparation kits, the SPRIselect reagent provides flexibility and control over the DNA size selection process with minimal lot-to-lot variance. Plus, it's stable at room temperature.
RNA and cDNA Cleanup
A flexible and highly reproducible method for purification :
Purifies cDNA and cRNA
Works for small and large nucleic adic products
No centrifugation or filtration required
Easily performed manually and automated
Sanger Dye Terminator Removal
Rapid, high-performance dye-terminator removal :
Based on SPRI technology
No centrifugation or filtration required
Easily performed manually or fully automated
Produces sequences with longer Phred 20 read lengths
Higher signal intensities than any other purification technology
