Virus Characterization in Pharma & Biotech Research

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Virus Genome Sequencing

Beckman Coulter AMPure XP SPRI cleanup chemistries NGS amplification RNAClean XP for cDNA cleanup


The genetic code of the 2019-nCoV-2 Corona virus was sequenced thanks to Next Generation Sequencing (NGS).   Beckman brings SPRI cleanup chemistries such as 
AMPure XP  (recognized as the “Gold Standard” for bead based) NGS amplification clean-up and RNAClean XP for cDNA cleanup to the market.      Watch the video 

Running genomic sequencing on such a large scale has enabled epidemiologists to track how the virus spreads, but running that many samples wouldn’t have been possible without automation.    Automated NGS library construction with the Biomek i-Series or Echo liquid handlers are two of the enabling platforms available at Beckman and Analis.      Watch the video

Virus Quantification 

IDENTIFY AND QUANTIFY VIRAL PROTEINS WITH CAPILLARY ELECTROPHORESIS - SCIEX

IDENTIFY AND QUANTIFY VIRAL PROTEINS WITH CAPILLARY ELECTROPHORESIS -  SCIEX

Read the scientific paper with this link " New capillary gel electrophoresis method for fast and accurate identification and quantification of multiple viral proteins in influenza vaccines" 

QUANTIFY INTACT VIRUS PARTICLES MORE PRECISELY AND FASTER THAN QPCR

An analytical quality by design (AQbD) approach was embraced for the development of a capillary zone electrophoresis (CZE) method for the quantification of intact virus particles. With CE, the intact adenovirus particles were separated from sample matrix components such as cell debris, residual cell DNA, proteins, and salts.    View on demand webinar 

Study of the Immunity Mechanisms

STUDY OF THE IMMUNITY MECHANISMS WITH  THE ADAPTATIVE FLOW CYTOMETER ​antibody cocktail DURACLONE

STUDY OF THE IMMUNITY MECHANISMS WITH  THE ADAPTATIVE FLOW CYTOMETER

 Standardization of flow Cytometry with the CytoFLEX analyzer and the ready-to-use antibody cocktail of DURACLONE
The Beckman Coulter 
CytoFLEX Platform is a revolutionary system presenting optimal excitation and emission, minimizing light loss and maximizing sensitivity. 
Download brochure
 
The dry 
DuraClone IM antibody panels are optimized for the identification and characterization of cells of the human immune system   Watch the video