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Automated NGS Library Preparation

 

Streamline NGS Library Prep with Beckman Coulter Automation

NGS library preparation is often time-consuming and error-prone. Manual pipetting can introduce inconsistencies and compromise precious samples.

Beckman Coulter offers automation solutions designed to address these challenges. By automating pipetting-intensive workflows, you can:


  • Minimize your hands-on time.
  • Improve your efficiency.
  • Increase the robustness of your results  

Benefits of Automation:

  • Enhanced accuracy: reduce human errors associated with 
       manual pipetting.
  • Improved reproducibility: consistent results across experiments.
  • Increased throughput: process more samples in less time.

 

Beckman Coulter's automation solutions

help streamline your NGS library prep and deliver reliable genetic analysis. The full range of automated liquid-handling solutions suits everyone — from small academic labs running their first preps to ultra-high-throughput sequencing centers. Whatever your throughput needs, Beckman has a robust automation solution.

LOW

<24 SAMPLES/BATCH 
BIOMEK i3 
Beckman Coulter BIOMEK i3
MORE INFO SOON

MEDIUM

24-48 SAMPLES/BATCH
BIOMEK i5  
BECKMAN COULTER Biomek i5LEARN MORE

HIGH

48+ SAMPLES/BATCH
BIOMEK i7

Beckman Coulter Biomek i7LEARN MORE        
                         

ULTRA-HIGH

384+ SAMPLES/BATCH
BIOMEK-Echo One 
   
BECKMAN COULTER Biomek Echo-OneLEARN MORE  

Beckman Coulter Life Sciences NGS Library Prep Workflow

Next Generation Sequencing is growing fast. As sequencing costs fall, NGS is becoming a common technique for knowledge discovery and disease research. Whatever your lab's throughput, NGS library prep is time-consuming and costly.

At lower throughput, automating with the Biomek i3-Series gives a fully automated, walk-away library prep solution. At higher throughput, combining the flexibility of a Biomek i-Series with the speed of an Echo Acoustic Liquid Handler saves time and reagent costs.

Whatever your target throughput, Beckman Coulter Life Sciences has an efficient solution.


Beckman Coulter NGS Library Prep Workflow infographics

Biomek i5 Span 8 NGS

This liquid handler is ideal for medium-throughput NGS workflows. 

Biomek i5 Span 8 NGS ideal for medium-throughput NGS workflows

It features:

 • Comprehensive automation: automate all tedious and repetitive NGS sample prep steps, from extraction to library construction.
• Enhanced efficiency: the Span 8 pipetting system and 360° rotating gripper ensure maximum efficiency and flexibility for full and partial plate processing.
• On-deck process control:  built-in shakers, Peltier elements and (optional) thermocyclers reduce hands-on time and increase throughput.
• Powerful software: use the Biomek software for intuitive method creation, a library of proven NGS protocols, and tools like Deck Optix™ for error prevention.

Benefits of the Biomek i5:

• Improved accuracy: minimize human error and ensure consistent sequencing results,
• Enhanced efficiency: streamline your workflow and save valuable resources,
• Increased Throughput: process more samples with less hands-on time.

Application in the spotlight :

Automating QIAseq® DIRECT enhanced Biomek i5 Span-8 AutomatedClick on picture to download this application

Ready to Elevate Your NGS Research? 
Contact us today to learn more about this Biomek and how it can transform your laboratory's NGS capabilities.       CONTACT US

Biomek i7 Hybrid NGS

Reliable automation for your high-throughput NGS library prep needs 

Beckman's Biomek i7 Hybrid NGSlibrary preparation

The Biomek i7 Hybrid NGS Workstation suits labs processing more than 48 samples per batch. It automates NGS sample preparation workflows end to end — extraction, library construction, qPCR, normalization and pooling.


Its dual pipetting — multi-channel and Span 8 — maximizes flexibility and efficiency.


It features:

Comprehensive Automation: streamline your entire NGS workflow with integrated on-deck process control elements such as shakers, Peltier’s, and (optional) thermocyclers.
Enhanced Productivity: strong reductions in hands-on time while boosting throughput and efficiency, ideal for high-throughput labs.
• Advanced Software: the Biomek software lets users create simple yet complete methods with strong intelligence and flexibility. It includes a library of proven NGS methods, each with intuitive interfaces and tools like Deck Optix™ for accurate setup and fewer costly errors.

Why Choose Biomek i7 Hybrid NGS Workstation?

• Flexibility: adapt to various NGS workflows with ease,
• Efficiency: Increase your lab’s productivity and throughput,
• Reliability: proven methods and advanced software to reduce errors and improve accuracy.
Discover the Biomek i7 Hybrid NGS Workstation and improve your NGS sample preparation. Contact us to learn more and book a demo.


Advanced Software -  Intuitive User Interfaces
Beckman Biomek i7 Advanced SoftwareClick on picture to watch the video

Application in the spotlight 
Automation of Single-Cell RNA-Seq Library Preparation using the Biomek i7   Click on picture to download this application 

Contact us today to learn more and schedule a demo.      CONTACT US

Biomek-Echo One

NGS library prep is no longer the bottle neck in ultra-high throughput NGS workflows

Beckman Coulter Biomek Echo One Ultra-high throughput NGS workflow

The Biomek Echo One combines the precision of acoustic liquid handling with the versatility of a Biomek workstation, delivering high efficiency and accuracy for genomics research.


Key Benefits:

•   High speed: the Echo 525 Acoustic Liquid Handler makes rapid, nanoliter-scale transfers, saving reagents and speeding up NGS workflows,
•   High accuracy: precise liquid handling without tips or contact, for reliable, reproducible results,
•   Versatility: the Biomek Echo One integrates with existing laboratory automation systems, providing flexibility for various NGS applications,
•   Efficiency: streamline your NGS workflow and reduce hands-on time,  so you can focus on more critical tasks.


Key Features:

•   Acoustic liquid handling: use sound energy for miniaturized, precise liquid transfers,

•   Biomek integration: combine the Echo with Biomek workstations for full automation of your NGS workflows,

•   Library preparation: automate essential steps like extraction, fragmentation, ligation, normalization and pooling,​

  Supporting tasks: centrifugation, shaking and thermal incubation for a complete walk-away NGS workflow.


Beckman's Biomek-Echo One Video Click on picture to watch the video 

Application in the spotlight :
Combining the Beckman Echo acoustic liquid handler and the Biomeki7 allowed us to greatly increase SARS-CoV-2 sequencing throughput.
Click on picture to download this application

Experience the Power of the Biomek Echo One


The Biomek Echo One suits scientists who want to optimize NGS experiments. By automating key steps and ensuring precise liquid handling, it saves reagents and delivers higher throughput with faster time to results.

Contact us to learn more about the Biomek Echo One and how it can improve your NGS research.

                           CONTACT US
 

  RELY ON SPRI  

SPRI (Solid Phase Reversible Immobilization) is a widely used method in next-generation sequencing (NGS) for library preparation and purification.


Beckman Coulter's reference SPRI products — AMPure XP, SPRIselect and RNAClean XP — support reliable NGS results.


SPRI (Solid Phase Reversible Immobilization) Click on picture to watch the video 

Beckman's SPRI beads offer several benefits for next-generation sequencing (NGS) applications:

  • High precision: SPRI beads bind nucleic acids selectively and reversibly by type and size, for strong performance in extracting, purifying, cleaning and size-selecting nucleic acids,
  • Automation-friendly: these paramagnetic beads automate easily on liquid handlers such as the Biomek i-Series, without centrifugation or filtration,

  • Reproducibility: the uniform bead size gives highly reproducible results, crucial for consistent NGS workflows,

  • Flexible size selection: SPRIselect reagents give control over DNA size selection, efficiently removing fragments outside the desired range,

  • High binding capacity: the high surface-area-to-mass ratio increases binding capacity, effective for various genomic applications,

  • Rapid purification: the fast magnetic response of SPRI beads allows rapid purifications, useful for high-throughput sequencing,

  • Minimal non-specific binding: the non-styrene polymer surface reduces non-specific binding, for cleaner samples downstream,


Together, these features make Beckman's SPRI beads a key tool for NGS workflows, delivering high-quality samples and supporting accurate sequencing.


Application in the spotlight :

NGS, Next Generation Sequencing, DNA Sequencing, Genome Sequencing, Illumina, Oxford Nanopore Technologies, Nanopore, Thermo, Pacific Biosciences, QIAseq, AMpureXP, SPRI, Biomek, Echo Click on picture to dowlnload this application

Contact us today to find out how our SPRI products contribute to the quality and efficiency of your NGS sample preparation.


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