Next Generation Sequencing (NGS)

NGS: Revolutionize Genetic Analysis with Rapid, Cost-Effective Sequencing

Next Generation Sequencing (NGS), also known as second-generation sequencing, has dramatically transformed the field of genetic analysis. By enabling the simultaneous sequencing of millions of DNA fragments, NGS has significantly reduced sequencing costs and expanded applications across various scientific disciplines.

Applications of NGS include:

  • Clinical research: Oncology, pathology, immunology, microbiology, virology, ...

  • Agricultural science: Crop improvement, disease resistance.

  • Environmental science: Biodiversity studies, pollution monitoring.

  • Forensic science: DNA profiling, crime scene investigation.

With its rapid and cost-effective sequencing capabilities, NGS is revolutionizing our understanding of genetics and its implications for human health, agriculture, and the environment.

Beckman Coulter Next Gen Sequencing Solutions Video

 

Streamline NGS Library Prep with Beckman Coulter Automation Solutions

NGS library preparation is often a time-consuming and error-prone process. Manual pipetting can introduce inconsistencies and compromise precious samples.

Beckman Coulter offers automation solutions designed to address these challenges. By automating pipetting-intensive workflows, you can:

Minimize your hands-on time.
Improve your efficiency.
• Increase the robustness of your results  

Benefits of Automation:


Enhanced accuracy: Reduce human errors associated with 
   manual pipetting.

Improved reproducibility: Ensure consistent results across experiments.

Increased throughput: Process more samples in less time.

Beckman Coulter's automation solutions

can help you streamline your NGS library prep process and deliver reliable genetic analysis results. They offer a full range of automated liquid handling solutions for customers in small academic laboratories, just starting out with their first few preps, to cutting-edge ultra-high-throughput sequencing powerhouses.  No matter what your throughput needs are, Beckman can deliver you a robust automation solution.

LOW

24 SAMPLES/BATCH 
BIOMEK NGeniuS 
Beckman Biomek NGeniuS
LEARN MORE

MEDIUM

24-48 SAMPLES/BATCH
BIOMEK i5  
BECKMAN COULTER Biomek i5LEARN MORE

HIGH

48+ SAMPLES/BATCH
BIOMEK i7

Beckman Coulter Biomek i7LEARN MORE        
                         

ULTRA-HIGH

384+ SAMPLES/BATCH
BIOMEK-Echo One 
   
BECKMAN COULTER Biomek Echo-OneLEARN MORE  

Beckmna Coulter NGS Library Prep Workflow

Biomek NGeniuS

Revolutionize your NGS library prep with this error-free, easy-to-use liquid handler.

Beckman Coulter NGeniuS NGS library prep automation

The Biomek NGeniuS Next Generation Library Prep System is a game-changer in NGS library preparation. Its error-reduction technology, ease-of-use, and minimal hands-on time make it the ideal choice for any type of research.
Designed for low throughput needs, this liquid handler offers batch flexibility with a variable number of samples per day (4 to 24 samples/batch). 
Enjoy out-of-the-box reagent aliquoting and error-free setup thanks to the ‘Dynamic DeckOptix’ feature.

Biomek NGeniuS: revolutionize your NGS library prep

The Cloud-based software allows you to monitor the system from anywhere using Google Chrome or Microsoft Edge. With a wide range of demonstrated NGS methods, the Biomek NGeniuS is the most effortless NGS liquid handler to set up and run. The applications roadmap features leading NGS kits for translational and oncology research.

Application in the spotlight

NGeniuS Illumina TruSight Oncology 500, TSO 500, NGS, Oncology
 Click on picture to download this application

Contact us today 
to see if the NGeniuS would be a fit for your lab.

CONTACT US

Biomek i5 Span 8 NGS

This liquid handler is ideal for medium-throughput NGS workflows. 

Biomek i5 Span 8 NGS ideal for medium-throughput NGS workflows

It features:

 • Comprehensive automation: automate all tedious and repetitive NGS sample prep steps, from extraction to library construction.
• Enhanced efficiency: the Span 8 pipetting system and 360° rotating gripper ensure maximum efficiency and flexibility for full and partial plate processing.
• On-deck process control: benefit from built-in shakers, Peltier’s, and (optional) thermocyclers for reduced hands-on time and increased throughput.
• Industry-leading software: leverage the powerful Biomek software for intuitive method creation, a repository of proven NGS protocols, and tools like Deck Optix™ for error prevention.

Experience the benefits of the Biomek i5:

• Improved accuracy: minimize human error and ensure consistent sequencing results,
• Enhanced efficiency: streamline your workflow and save valuable resources,
• Increased Throughput: process more samples with less hands-on time.

Application in the spotlight :

Automating QIAseq® DIRECT enhanced Biomek i5 Span-8 AutomatedClick on picture to download this application

Ready to Elevate Your NGS Research? 
Contact us today to learn more about this Biomek and how it can transform your laboratory's NGS capabilities.       CONTACT US

Biomek i7 Hybrid NGS

Reliable automation for your high-throughput NGS library prep needs 

Beckman's Biomek i7 Hybrid NGSlibrary preparation

The Biomek i7 Hybrid NGS Workstation is the ultimate solution for labs that require more than 48 samples / batch. The Biomek i7 automates any Next-Generation Sequencing (NGS) sample preparation workflows, from extraction to library construction, qPCR, normalization, and pooling. 

The Biomek i7 workstation maximizes flexibility and efficiency with its dual pipetting capabilities—multi-channel and Span 8. 

It features:

Comprehensive Automation: streamline your entire NGS workflow with integrated on-deck process control elements such as shakers, Peltier’s, and (optional) thermocyclers.
Enhanced Productivity: achieve significant reductions in hands-on time while boosting throughput and efficiency, ideal for high-throughput laboratories.
• Advanced Software: the industry leading Biomek software empowers users to create simple yet comprehensive methods with unmatched intelligence and flexibility. Benefit from a repository of demonstrated NGS methods, each featuring intuitive User Interfaces and tools like Deck Optix™ to ensure accurate setup and minimize costly errors.

Why Choose Biomek i7 Hybrid NGS Workstation?

• Flexibility: Adapt to various NGS workflows with ease,
• Efficiency: Increase your lab’s productivity and throughput,
• Reliability: Depend on proven methods and advanced software to reduce errors and enhance accuracy.
Explore the Biomek i7 Hybrid NGS Workstation and revolutionize your NGS sample preparation. Contact us today to learn more and schedule a demo.

Advanced Software -  Intuitive User Interfaces
Beckman Biomek i7 Advanced SoftwareClick on picture to watch the video

Application in the spotlight 
Automation of Single-Cell RNA-Seq Library Preparation using the Biomek i7   Click on picture to download this application 

Contact us today to learn more and schedule a demo.      CONTACT US

Biomek-Echo One

NGS library prep is no longer the bottle neck in ultra-high throughput NGS workflows

Beckman Coulter Biomek Echo One Ultra-high throughput NGS workflow

The Biomek Echo One is a ground-breaking platform that redefines the possibilities of NGS sample preparation. Combining the precision of acoustic liquid handling with the versatility of a Biomek workstation, this instrument offers unparalleled efficiency and accuracy for your genomics research.

Key Benefits:

•   Unmatched speed: the Echo 525 Acoustic Liquid Handler's innovative technology enables rapid, nanoliter-scale transfers, significantly saving reagents and accelerating your NGS workflows,
•   Exceptional accuracy: enjoy precise liquid handling without the need for tips or contact, ensuring reliable and reproducible results,
•   Versatility: the Biomek Echo One seamlessly integrates with existing laboratory automation systems, providing flexibility for various NGS applications,
•   Efficiency: streamline your NGS workflow and reduce hands-on time, allowing you to focus on more critical tasks.


Key Features:

•   Acoustic liquid handling: leverage the power of sound energy for miniaturized precise liquid transfers,

•   Biomek integration: seamlessly combine the Echo with Biomek workstations for full automation of your NGS workflows,

•   Library preparation: automate essential steps like extraction, fragmentation, ligation, normalization, and pooling,

•   supporting tasks: perform centrifugation, shaking, and thermal incubation for a complete walk away NGS workflow.

Beckman's Biomek-Echo One Video Click on picture to watch the video 

Application in the spotlight :
Combining the Beckman Echo acoustic liquid handler and the Biomeki7 allowed us to greatly increase SARS-CoV-2 sequencing throughput.
Click on picture to download this application

Experience the Power of the Biomek Echo One

The Biomek Echo One is the ideal choice for scientists seeking to optimize their NGS experiments. By automating key steps and ensuring precise liquid handling, this instrument helps you to save on reagents, achieve higher throughput with faster time-to-results.
Contact us today to learn more about the Biomek Echo One and how it can revolutionize your NGS research.                           CONTACT US
 

  RELY ON SPRI  

SPRI (Solid Phase Reversible Immobilization) is a widely used method in next-generation sequencing (NGS) for library preparation and purification. 


Using Beckman Coulter’s gold standard SPRI products, AMPure XP, SPRIselect and RNAClean XP for NGS are your assurance to reliable NGS results. 

SPRI (Solid Phase Reversible Immobilization) Click on picture to watch the video 

Beckman’s SPRI beads offer several benefits for next-generation sequencing (NGS) applications: 

•  High precision: SPRI beads selectively and reversibly bind nucleic acids based on their type and size, ensuring high performance in extracting, purifying, cleaning, and size-selecting nucleic acids,
•  Automation-friendly: these paramagnetic beads can be easily automated on liquid handlers, such as the Biomek i-Series automated workstations, without the need for centrifugation or filtration,
•  Reproducibility: the uniform bead size ensures highly reproducible results, which is crucial for consistent NGS workflows,
•  Flexibility in size selection: SPRIselect reagents provide flexibility and control over the DNA size selection process, allowing for efficient removal of fragments outside the desired size range,
•   High binding capacity: the high surface area to mass ratio of the beads increases their binding capacity, making them effective for various genomic applications,
•   Rapid purification: the fast magnetic response time of SPRI beads allows for rapid purifications, which is beneficial for high-throughput sequencing,
•  Minimal non-specific binding: the non-styrene polymer surface of the beads reduces non-specific binding, ensuring cleaner samples for downstream applications,

These features make Beckman’s SPRI beads an indispensable tool for NGS workflows, providing high-quality samples and supporting accurate sequencing results.

Application in the spotlight :

NGS, Next Generation Sequencing, DNA Sequencing, Genome Sequencing, Illumina, Oxford Nanopore Technologies, Nanopore, Thermo, Pacific Biosciences, QIAseq, AMpureXP, SPRI, Biomek, Echo Click on picture to dowlnload this application

Contact us today to find out how our SPRI products contribute to the quality and efficiency of your NGS sample preparation.


CONTACT US


 

Related product categories