Vaccine Development in Pharma & Biotech Research

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CO2 INCUBATORS - MEMMERT

The control system of the Memmert CO2 incubator ICOmed is so finely tuned that the appliance reaches the setpoint temperature very quickly and without temperature overshoots.

SHAKER INCUBATORS - LABWIT

Ultimate-Cell stackable shaking incubator is the comprehensive solution with temperature, shaking speed, and optional features, e.g. CO2, humidity controls.  

MICROBIOREACTORS - BECKMAN

The BioLector XT microbioreactor accelerates evaluation of diverse organisms, including anaerobes. Up to 48 parallel vessels in milliliter-scale support robust, real-time evaluation of biomass, fluorescence and other key cultivation parameters to share deeper insights into bioprocess development.  

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HARVESTING WITH HIGH CAPACITY CENTRIFUGES  - BECKMAN COULTER & SIGMA 

PURIFICATION  - BECKMAN COULTER

• Purify viruses from cultures or human samples
• Prepare plasmids for virus production
• Purify viral material for vaccine development (by ULTRACENTRIFUGES & HIGH PERFORMANCE CENTRIFUGES)

MANUAL LIQUID HANDLING - HTL

Start your experiments with success thanks to the manual liquid handling  portfolio from HTL.

AUTOMATED LIQUID HANDLING - BECKMAN COULTER  

• The Beckman automation platforms  are there to assist you in every step of your vaccine development process, whether you are in development, needing to construct numerous antibodies, or using cell lines within your process, automation can help you to achieve more in less time. If you need to run ELISA experiments further in your development process, we have the skills and support team to assist you.

• Cell line development   - Development of stable or transient cell lines for the production of purified antigens can be automated using 21 CFR Part 11-supported Biomek i-Series automated liquid handlers.
• Antibody construction  - Synthetic antibody construction by miniaturizing isothermal DNA assembly is enabled thanks to the Echo 525.
• Antibody Engineering  - Antibody engineering using  hybridoma  based technology to make antibodies and evaluate their specificity with  ELISA  using an end-to-end Biomek i-Series-based system.

LIQUID HANDLING CALIBRATION & VERIFICATION SYSTEMS -  ARTEL 

ONLINE O2 ,PH, BIOMASS ANALYSIS WITH OPTICAL SENSORS -  PRESENS

BIOANALYTE (GLU, LACT, ELECTROLYTES,CO2,..)  - BECKMAN COULTER

Test samples quickly, easily and accurately—keeping your test cell cultures in balance, viable and growing.  Watch the video

CHECK CELL GROWTH IN BSL 3-4 LABS  - IPRASENSE

Simple Life Cell Imaging system to stay safe & save time by not having to enter the laboratory and get dressed.  See note

CELL COUNTING & VIABILITY  - BECKMAN COULTER

Automated, Easy, Quick, Reliable. Discover  The new Vi-CELL BLU :  Watch the video

CELL & PARTICLE DETECTION & SIZE - BECKMAN COULTER

Coulter Counter  Multisizer 4E counts and measures every single particle and change in size in a measuring solution (including cells, bacteria or microparticles). 

FLOW CYTOMETRY -  BECKMAN COULTER

Study of the immunity mechanisms with the adaptative flow cytometer BECKMAN COULTER CytoFlex and a ready-to-use cocktail DURACLONE.  Watch the video - Brochure - Article

AGGREGATION, MOLECULAR INTERACTION, VIRAL CAPSID GENETIC LOAD - BECKMAN COULTER

• Viral Capsid Genetic Load Control  by AUC. Quantify ratio of full, empty, & partially-full capsid. Gold standard, higher-resolution  (Watch Webinar)
• Interactions viral protein/nucleic acid/ human protein, virus replication cycle with the versatile AUC biophysical technology. 
  

CAPILLARY ELECTROPHORESIS  - SCIEX

Get fast, accurate results for gene therapies and oligonucleotides.

PARTICLE CHARACTERIZATION -  Beckman Coulter 

The Beckman Coulter LS measures particles in nearly any suspension as well as particles dispersed in air. Measurement range of 10 nm - 3500 µm. Dry Powder System (400 nm - 3500 µm). Universal Liquid module (10 nm-2000 µm). Already used for the production and quantification of (dry powder) vaccines (influenza and norovirus)

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BIOSAFE CLINICAL CENTRIFUGES  - SIGMA

FLOW CYTOMETRY  - BECKMAN COULTER

Study of the immunity mechanisms with the adaptative flow cytometer BECKMAN COULTER CytoFlex and a ready-to-use cocktail DURACLONE.
Watch the video        Brochure
Article: Cossarizza, A., De Biasi, S., Guaraldi, G., Girardis, M., Mussini, C. and (2020), SARS‐CoV‐2, the Virus that Causes COVID‐19: Cytometry and the New Challenge for Global Health. Cytometry, 97: 340-343. doi:10.1002/cyto.a.24002

In the coming weeks, the biggest challenge with regard to COVID-19  will be the preservation of the cold vaccine supply chain.
Everyone knows that any failure in this chain would be disastrous for the effectiveness of the vaccines. Thanks to its large equipment range, Analis provides complete and integrated solutions for :

• REFRIGERATORS +4°C

• FREEZERS -20°C

• ULTRA FREEZERS -80°C

• CRYOGENIC STORAGE -196°C